Toxicity Sub chronic Water Extract Meretrix meretrix Linnaeus In Vivo on Sprague dawley Rats

  • Azwin Apriandi Program Studi Teknologi Hasil Perikanan, Fakultas Ilmu Kelautan dan Perikanan, Universitas Maritim Raja Ali Haji. Jalan Politeknik Senggarang, Kampus UMRAH Senggarang Tanjungpinang, Kepulauan Riau, Hp. +6281289009825
  • Kustiariyah Tarman Departemen Teknologi Hasil Perairan, Fakultas Perikanan dan Ilmu Kelautan, Institut Pertanian Bogor. Jalan Lingkar Akademik, Kampus IPB Dramaga 16680
  • Purwantiningsih Sugita Departemen Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Institut Pertanian Bogor. Jalan Lingkar Akademik, Kampus IPB Dramaga 16680
Keywords: blood chemistry, Meretrix meretrix, Sprague dawley rats, water extract

Abstract

Meretrix meretrix is one of the shells of sea water are widely utilized by people as food. This clam
also has many properties and benefits, so in this study tested the effect of the water extract of Meretrix
meretrix against blood chemistry profile Sprague Dawley rats with the method (OECD 413: 2009). Based on
observations obtained growth, feed intake, weight of liver and kidney in normal conditions. Levels of urea,
creatinine, cholesterol between the control mice treated with A/0.1 and A/1 were not significantly different
(p> 0.05) while the levels of bilirubin and albumin between control mice treated with A/0.1 and A/1 results
significantly different (p<0.05), but all blood chemistry parameters tested is still in the normal category.

Published
2016-08-30